Capillary Electrophoresis Systems and Accessories
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Medchemexpress LLC DDP-38003 trihydrochloride | 2319789-94-9 | 98.0% | 459.84 | 1 MG
DDP-38003 trihydrochloride is a novel, orally available inhibitor of histone lysine-specific demethylase 1A (KDM1A/LSD1) with an IC50 of 84 nM. It exhibits in vivo efficacy after oral administration, leading to increased survival in mouse leukemia models with evidence of KDM1A inhibition. It is considered a potential oral anticancer agent.
- Novel, orally available inhibitor of histone lysine-specific demethylase 1A (KDM1A/LSD1)
- IC50 of 84 nM against KDM1A
- More active in reducing colony-forming ability and inducing differentiation of THP-1 cells compared to the 1R, 2S analogue
- Exhibits in vivo efficacy after oral administration
- Increases survival in mouse leukemia models (62% increase)
- Half-life of 8 hours
- Potential oral anticancer agent
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Microsolv Technology Corporation Capillary Zero Flow 50Um X 1M
Capillary, Zero Flow, 50um ID by 1 meter. MicroSolv Brand. 1/EA.
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Revvity Health Sciences Inc DNA 5K / RNA / Charge Variant Assay LabChip (bulk value 4 pack)
DNA 5K / RNA / Charge Variant Assay LabChip (bulk value 4 pack)
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